She was born on December 21, 1954, in Ironton, Ohio, to the late Kenneth and Lorrie Watson. She was also preceded in death by the love of her life, her husband Mark R. Blake, whom she married on September 5, 1972.
Brenda was a 1972 graduate of South Webster High School. She was a member of Bloom Free Will Baptist Church and attended Union Free Will Baptist Church. She retired after 25 years as a Medical Receptionist.
Brenda is survived by a son, Rob Blake, and wife Patty, a daughter Kelly Gleim and husband Daniel, all of Wheelersburg, and a grandson, Elijah Blake, who was her pride and joy.